Peptide Chemicals


Amino Acid Derivatives and Preloaded Resins

Please have a look at our Catalog. For more comfortable viewing, please right click on the link and chose "save target as..." to download the full pdf to your harddrive.
Alternatively, feel free to request a printed copy!

Proprietary know-how in single step tert. Butylation technology at ORPEGEN Peptide Chemicals provides production of all N-protected amino acid tert. Butylation derivates at competitive prices. The flexibility in reactor capacity ensures bulk production of important protected amino acids.

  • Fmoc, Boc, Ddz and Z Amino Acids
  • Pre-loaded Wang resins and otherwise linked amino acids on polymer support.

The manufacturing of the amino acid derivates is performed in glass or stainless steel reactors and delivers up to 200 kg per batch. ORPEGEN Peptide Chemicals uses only raw materials and solvents of highest quality after passing rigorous quality control procedures. Each lot of amino acid derivatives manufactured is checked for enantiomeric purity, acetate and beta-alanine content, and is accompanied by a BSE/TSE-risk free certificate.


Custom Peptide Synthesis

ORPEGEN Peptide Chemicals has in house pharmaceutical GMP production capacity and know how for generic synthetic peptide hormones (examples: Oxytocin, LHRH, Somatostatin, Eledoisin, MCD-Peptide, Calcitonin, Bradykinin, Nociceptin) and thymic peptides, e.g. Thymosin-a1, Twin- a1 and Thymosin-a1 related shorter peptides, antigenic determinants).

We specialize in covering the stretch of lab scale development to kg scale GMP production and usually accompany our customers through the preclinical development, the clinical phases I to III and later routine GMP production.

All this capacity is based on in-house manufacture of more than 350 amino acid derivates at industrial scale.

Solid and Solution Phase Peptide Synthesis

  • Large Scale Solid Phase Peptide Synthesis (kg to mg) on all common polymer supports
  • Multiple kg-synthesis of Peptides in solution
  • Optimized chemical strategies Fmoc-/ tert.Butyl, Boc-/Benzyl, Z-/ tert.Butyl, Ddz-/ tert.Butyl, based on ORPEGEN Pharma pharmaceutical grade amino acid derivatives.

Chemically Modified Peptides
  • Glycosylation
  • Biotinylation
  • Palmitinoylation, Pegylation and others